Pure , Ultra-Clean Chitosan

Description
The ChitoLytic Chitosan – Pure Ultra-Clean Chitosan (cc-PUC) is a Depyrogenated, Terminally Sterile, and Endotoxin-Free chitosan. Its recommended for applications that uses chitosan for implantation and/or parenteral injection.
It forms gels with multivalent anions and clear solutions that dry to strong, clear films. Its ideal for scaffolds, cell therapy, drug delivery, and biomedical applications.
Its a natural biopolmer that’s biocompatible, biodegradable, antibacterial, an adhesive to tissue, and can be used in a variety of applications, e.g.,
Biomedical devices
Micro and Nanoencapsulation for controlled release in drug delivery and other therapeutics
Implants
Injectables
cc-PUC goes through this process to achieve a validated pure ultra-clean chitosan;
Clean starting raw material
Processing of the base chitosan from chitin to achieve a pure highly deacetylated and clean chitosan
Testing-1&2 – it’s then validated through a first-phase internal and independent 3rd party assay testing
Plasma-Treated – it’s then treated with a depyrongenated, non-thermal plasma treatment to further remove heavy metals and bioburdens. The chitosan is fully depyrogenated, including the complete removal of endotoxin
Testing-3 – a second phase of independent 3rd party testing is performed to validate the removal of endotoxin
The Plasma-Treatment technology provides consistent results of an endotoxin specification of <1.0 EU/g. Following the plasma treatment, the underlying chitosan remains intact compositionally and functionally.